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In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

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From an experimental perspective, this means that BPC-157 can be used as a tool to study angiogenesis, endothelial signaling and the organization of the vascular response in in vitro and in vivo models